RAYOsXf6wL
Full identifier: http://purl.org/np/RAYOsXf6wLjW5R7f7Sjg4bjbYzKnxF5hS7EPHa73sCnP4
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Status
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Nanopublication
https://w3id.org/biolink/vocab/actively_involved_in
actively_involved_in
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"actively involved in - holds between a continuant and a process or function, where the continuant actively contributes to part or all of the process or function it realizes"
.
https://w3id.org/biolink/vocab/affects
affects
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"affects - describes an entity that has a direct affect on the state or quality of another existing entity. Use of the 'affects' predicate implies that the affected entity already exists, unlike predicates such as 'affects risk for' and 'prevents, where the outcome is something that may or may not come to be."
.
https://w3id.org/biolink/vocab/ameliorates
ameliorates
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"ameliorates - A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure, clinical intervention) and a condition (a phenotype or disease), where the presence of the entity reduces or eliminates some or all aspects of the condition."
.
https://w3id.org/biolink/vocab/assesses
assesses
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"assesses - The effect of a thing on a target was interrogated in some assay. A relationship between some perturbing agent (usually a chemical compound) and some target entity, where the affect of the perturbing agent on the target entity was interrogated in a particular assay. The target might be a particular protein, tissue, phenotype, whole organism, cell line, or other type of biological entity."
.
https://w3id.org/biolink/vocab/associated_with
associated_with
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"associated with - Expresses a relationship between two named things where the relationship is typically generated statistically (though not in all cases), and is weaker than its child, 'correlated with', but stronger than its parent, 'related to'. This relationship holds between two concepts represented by variables for which a statistical dependence is demonstrated. E.g. the statement “Atrial Fibrillation (Afib) is associated with Myocardial Infarction (MI)” asserts that having Afib is not statistically independent from whether a patient will also have MI. Note that in Translator associations, the subject and object concepts may map exactly to the statistical variables, or represent related entities for which the variables serve as proxies in an Association (e.g. diseases, chemical entities or processes)."
.
https://w3id.org/biolink/vocab/associated_with_decreased_likelihood_of
associated_with_decreased_likelihood_of
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"associated with decreased likelihood of - Expresses a relationship between two named things where the relationship is typically generated statistically and the state or fact of something is less probable."
.
https://w3id.org/biolink/vocab/associated_with_increased_likelihood_of
associated_with_increased_likelihood_of
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"associated with increased likelihood of - Expresses a relationship between two named things where the relationship is typically generated statistically and the state or fact of something is more probable."
.
https://w3id.org/biolink/vocab/associated_with_likelihood_of
associated_with_likelihood_of
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"associated with likelihood of - A a relationship that holds between two concepts represented by variables for which a statistical dependence is demonstrated, wherein the state or value of one variable predicts the future state or value of the other. E.g. the statement “An Atrial Fibrillation (Afib) diagnosis is associated with likelihood of a Myocardial Infarction (MI) diagnosis” asserts that the state of having Afib is associated with an increased or decreased likelihood that a patient will later exhibit MI."
.
https://w3id.org/biolink/vocab/associated_with_resistance_to
associated_with_resistance_to
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"associated with resistance to - A relation that holds between a named thing and a chemical that specifies that the change in the named thing is found to be associated with the degree of resistance to treatment by the chemical."
.
https://w3id.org/biolink/vocab/associated_with_sensitivity_to
associated_with_sensitivity_to
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"associated with sensitivity to - A relation that holds between a named thing and a chemical that specifies that the change in the named thing is found to be associated with the degree of sensitivity to treatment by the chemical."
.
https://w3id.org/biolink/vocab/biomarker_for
biomarker_for
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"biomarker for - holds between a measurable chemical entity and a disease or phenotypic feature, where the entity is used as an indicator of the presence or state of the disease or feature."
.
https://w3id.org/biolink/vocab/chemically_similar_to
chemically_similar_to
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"chemically similar to - holds between one small molecule entity and another that it approximates for purposes of scientific study, in virtue of its exhibiting similar features of the studied entity."
.
https://w3id.org/biolink/vocab/condition_associated_with_gene
condition_associated_with_gene
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"condition associated with gene - holds between a gene and a disease or phenotypic feature that may be influenced, contribute to, or be correlated with the gene or its alleles/products"
.
https://w3id.org/biolink/vocab/correlated_with
correlated_with
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"correlated with - A relationship that holds between two concepts represented by variables for which a statistical dependence is demonstrated using a correlation analysis method."
.
https://w3id.org/biolink/vocab/decreases_amount_or_activity_of
decreases_amount_or_activity_of
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"decreases amount or activity of - A grouping mixin to help with searching for all the predicates that decrease the amount or activity of the object."
.
https://w3id.org/biolink/vocab/decreases_response_to
decreases_response_to
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"decreases response to - holds between two chemical entities where the action or effect of one decreases the susceptibility of a biological entity or system (e.g. an organism, cell, cellular component, macromolecular machine mixin, biological or pathological process) to the other"
.
https://w3id.org/biolink/vocab/derives_from
derives_from
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"derives from - holds between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity"
.
https://w3id.org/biolink/vocab/derives_into
derives_into
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"derives into - holds between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity"
.
https://w3id.org/biolink/vocab/directly_physically_interacts_with
directly_physically_interacts_with
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"directly physically interacts with - A causal mechanism mediated by a direct contact between the effector and target entities (this contact may be weak or strong, transient or stable)."
.
https://w3id.org/biolink/vocab/disease_has_location
disease_has_location
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"disease has location - A relationship between a disease and an anatomical entity where the disease has one or more features that are located in that entity."
.
https://w3id.org/biolink/vocab/exacerbates
exacerbates
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"exacerbates - A relationship between an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) and a condition (a phenotype or disease), where the presence of the entity worsens some or all aspects of the condition."
.
https://w3id.org/biolink/vocab/food_component_of
food_component_of
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"food component of - holds between a one or more chemical entities present in food, irrespective of nutritional value (i.e. could also be a contaminant or additive)"
.
https://w3id.org/biolink/vocab/gene_associated_with_condition
gene_associated_with_condition
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"gene associated with condition - holds between a gene and a disease or phenotypic feature that the gene or its alleles/products may influence, contribute to, or correlate with"
.
https://w3id.org/biolink/vocab/gene_fusion_with
gene_fusion_with
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"gene fusion with - holds between two independent genes that have fused through translocation, interstitial deletion, or chromosomal inversion to form a new, hybrid gene. Fusion genes are often implicated in various neoplasms and cancers."
.
https://w3id.org/biolink/vocab/gene_product_of
gene_product_of
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"gene product of - definition x has gene product of y if and only if y is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of thatf process is either y or something that is ribosomally translated from x"
.
https://w3id.org/biolink/vocab/genetically_interacts_with
genetically_interacts_with
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"genetically interacts with - holds between two genes whose phenotypic effects are dependent on each other in some way - such that their combined phenotypic effects are the result of some interaction between the activity of their gene products. Examples include epistasis and synthetic lethality."
.
https://w3id.org/biolink/vocab/has_adverse_event
has_adverse_event
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"has adverse event - An untoward medical occurrence in a patient or clinical investigation subject that happens during treatment with a therapeutic agent. Adverse events may be caused by something other than the drug or therapy being given and may include abnormal laboratory finding, symptoms, or diseases temporally associated with the treatment, whether or not considered related to the treatment. Adverse events are unintended effects that occur when a medication is administered correctly."
.
https://w3id.org/biolink/vocab/has_biomarker
has_biomarker
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"has biomarker - holds between a disease or phenotypic feature and a measurable chemical entity that is used as an indicator of the presence or state of the disease or feature. # metabolite"
.
https://w3id.org/biolink/vocab/has_food_component
has_food_component
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"has food component - holds between food and one or more chemical entities composing it, irrespective of nutritional value (i.e. could also be a contaminant or additive)"
.
https://w3id.org/biolink/vocab/has_mode_of_inheritance
has_mode_of_inheritance
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"has mode of inheritance - Relates a disease or phenotypic feature to its observed genetic segregation and assumed associated underlying DNA manifestation (i.e. autosomal, sex or mitochondrial chromosome)."
.
https://w3id.org/biolink/vocab/has_phenotype
has_phenotype
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"has phenotype - holds between a biological entity and a phenotype, where a phenotype is construed broadly as any kind of quality of an organism part, a collection of these qualities, or a change in quality or qualities (e.g. abnormally increased temperature). In SNOMEDCT, disorders with keyword 'characterized by' should translate into this predicate."
.
https://w3id.org/biolink/vocab/has_plasma_membrane_part
has_plasma_membrane_part
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"has plasma membrane part - Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part."
.
https://w3id.org/biolink/vocab/has_sequence_location
has_sequence_location
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"has sequence location - holds between two nucleic acid entities when the subject can be localized in sequence coordinates on the object. For example, between an exon and a chromosome/contig."
.
https://w3id.org/biolink/vocab/has_side_effect
has_side_effect
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"has side effect - An unintended, but predictable, secondary effect shown to be correlated with a therapeutic agent, drug or treatment. Side effects happen at normal, recommended doses or treatments, and are unrelated to the intended purpose of the medication."
.
https://w3id.org/biolink/vocab/increases_amount_or_activity_of
increases_amount_or_activity_of
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"increases amount or activity of - A grouping mixin to help with searching for all the predicates that increase the amount or activity of the object."
.
https://w3id.org/biolink/vocab/increases_response_to
increases_response_to
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"increases response to - holds between two chemical entities where the action or effect of one increases the susceptibility of a biological entity or system (e.g. an organism, cell, cellular component, macromolecular machine mixin, biological or pathological process) to the other"
.
https://w3id.org/biolink/vocab/is_active_ingredient_of
is_active_ingredient_of
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"is active ingredient of - holds between a molecular entity and a drug, in which the former is a part of the latter, and is a biologically active component"
.
https://w3id.org/biolink/vocab/is_frameshift_variant_of
is_frameshift_variant_of
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"is frameshift variant of - holds between a sequence variant and a gene, such the sequence variant causes a disruption of the translational reading frame, because the number of nucleotides inserted or deleted is not a multiple of three."
.
https://w3id.org/biolink/vocab/is_missense_variant_of
is_missense_variant_of
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"is missense variant of - holds between a gene and a sequence variant, such the sequence variant results in a different amino acid sequence but where the length is preserved."
.
https://w3id.org/biolink/vocab/is_splice_site_variant_of
is_splice_site_variant_of
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"is splice site variant of - holds between a sequence variant and a gene, such the sequence variant is in the canonical splice site of one of the gene's exons."
.
https://w3id.org/biolink/vocab/is_synonymous_variant_of
is_synonymous_variant_of
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"is synonymous variant of - holds between a sequence variant and a gene, such the sequence variant is in the coding sequence of the gene, but results in the same amino acid sequence"
.
https://w3id.org/biolink/vocab/manifestation_of
manifestation_of
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"manifestation of - that part of a phenomenon which is directly observable or visibly expressed, or which gives evidence to the underlying process; used in SemMedDB for linking things like dysfunctions and processes to some disease or syndrome"
.
https://w3id.org/biolink/vocab/negatively_correlated_with
negatively_correlated_with
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"negatively correlated with - A relationship that holds between two concepts represented by variables for which a statistical correlation is demonstrated, wherein variable values move in opposite directions (i.e. increased in one or presence of one correlates with a decrease or absence of the other)."
.
https://w3id.org/biolink/vocab/occurs_together_in_literature_with
occurs_together_in_literature_with
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"occurs together in literature with - holds between two entities where their co-occurrence is correlated by counts of publications in which both occur, using some threshold of occurrence as defined by the edge provider."
.
https://w3id.org/biolink/vocab/opposite_of
opposite_of
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"opposite of - x is the opposite of y if there exists some distance metric M, and there exists no z such as M(x,z) <= M(x,y) or M(y,z) <= M(y,x). (This description is from RO. Needs to be rephrased)."
.
https://w3id.org/biolink/vocab/physically_interacts_with
physically_interacts_with
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"physically interacts with - holds between two entities that make physical contact as part of some interaction. does not imply a causal relationship."
.
https://w3id.org/biolink/vocab/positively_correlated_with
positively_correlated_with
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"positively correlated with - A relationship that holds between two concepts represented by variables for which a statistical correlation is demonstrated, wherein variable values move together in the same direction (i.e. increased in one or presence of one correlates with an increase or presence of the other)."
.
https://w3id.org/biolink/vocab/prevents
prevents
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"prevents - holds between an entity whose application or use reduces the likelihood of a potential outcome. Typically used to associate a chemical entity, exposure, activity, or medical intervention that can prevent the onset a disease or phenotypic feature."
.
https://w3id.org/biolink/vocab/regulates
regulates
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"regulates - A more specific form of affects, that implies the effect results from a biologically evolved control mechanism. Gene-affects-gene relationships will (almost) always involve regulation. Exogenous/environmental chemical-affects-gene relationships are not cases of regulation in this definition. Instead these would be captured using the 'affects' predicate, or possibly one of the 'interacts with' predicates depending on the nature of the interaction."
.
https://w3id.org/biolink/vocab/response_affected_by
response_affected_by
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"response affected by - holds between two chemical entities where the susceptibility of a biological entity or system (e.g. an organism, cell, cellular component, macromolecular machine mixin, biological or pathological process) of one is affected by the action of the other."
.
https://w3id.org/biolink/vocab/translates_to
translates_to
http://www.w3.org/2000/01/rdf-schema#label
label
(this is a literal)
"translates to - x (amino acid chain/polypeptide) is the ribosomal translation of y (transcript) if and only if a ribosome reads y (transcript) through a series of triplet codon-amino acid adaptor activities (GO:0030533) and produces x (amino acid chain/polypeptide)"
.
This is the identifier for the assertion of this nanopublication.
http://purl.org/np/RAYOsXf6wL...#assertion
The assertion above
http://www.w3.org/ns/prov#wasDerivedFrom
wasDerivedFrom
https://raw.githubusercontent....model/master/biolink-model.ttl
biolink-model.ttl
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAYOsXf6wL...#sig
sig
http://purl.org/nanopub/x/hasSignatureTarget
has as target
This is the identifier for this whole nanopublication.
http://purl.org/np/RAYOsXf6wL...
this nanopublication
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAYOsXf6wL...#sig
sig
http://purl.org/nanopub/x/hasAlgorithm
has the algorithm
(this is a literal)
"RSA"
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAYOsXf6wL...#sig
sig
http://purl.org/nanopub/x/hasPublicKey
has the public key
(this is a literal)
"MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCwUtewGCpT5vIfXYE1bmf/Uqu1ojqnWdYxv+ySO80ul8Gu7m8KoyPAwuvaPj0lvPtHrg000qMmkxzKhYknEjq8v7EerxZNYp5B3/3+5ZpuWOYAs78UnQVjbHSmDdmryr4D4VvvNIiUmd0yxci47dTFUj4DvfHnGd6hVe5+goqdcwIDAQAB"
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAYOsXf6wL...#sig
sig
http://purl.org/nanopub/x/hasSignature
has the signature
(this is a literal)
"nocA3xyh0CvM82EZ5G/AI5LY/kZbnXVDn7nvVTbygAG94a4hx8ScsqoszVxQWMyOlyhGwvjgU6i8wFvGzzU7WwrhPHNaRfRbmuqRruq3s0dVX7Pm5p6JaQgUMefAj488BWRFctspqyqQTxEqn05/xBhhg+8JxkAn1yLg2TCKG4o="
.
This is the identifier for this whole nanopublication.
http://purl.org/np/RAYOsXf6wL...
this nanopublication
http://purl.org/dc/terms/creator
creator
https://orcid.org/0000-0002-1267-0234
Tobias Kuhn
.