association
Full identifier: http://purl.org/np/RAHesFs45OdICLlRnaAcWyoLQpAkznGB7uTtc3Ksbrke0#association
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Minted in Nanopublication
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAHesFs45O...#association
This association
http://www.w3.org/2000/01/rdf-schema#label
has label
(this is a literal)
"indications and usage neoplastic disease methotrexate is indicated in the treatment of gestational choriocarcinoma chorioadenoma destuens and hydatidiform mole methotrexate is used in maintenance therapy in combination with other chemotherapeutic agents methotrexate is used alone or in combination with other anticancer agents in the treatment of breast cancer epidermoid cancers of the head and neck advanced mycosis fungoides cutaneous t cell lymphoma and lung cancer particularly squamous cell and small cell types methotrexate is also used in combination with other chemotherapeutic agents in the treatment of advanced stage non hodgkin s lymphomas psoriasis methotrexate is indicated in the symptomatic control of severe recalcitrant disabling psoriasis that is not adequately responsive to other forms of therapy but only when the diagnosis has been established as by biopsy and or after dermatologic consultation it is important that a psoriasis flare is not due to an undiagnosed concomitant disease affecting immune responses rheumatoid arthritis including polyarticular course juvenile rheumatoid arthritis methotrexate is indicated in the management of selected adults with severs active rheumatoid arthritis acr criteria or children with active polyarticular course juvenile rheumatoid arthritis who have had an insufficient therapeutic response to or are intolerant of an adequate trial of first line therapy including full dose non steroidal antiinflammatory agents nsaids aspirin nsaids and or low dose steroids may be continued although the possibility of increased toxicity with concomitant use of nsaids including salicylates has not been fully explored see precautions drug interactions steroids may be reduced gradually in patients who respond to methotrexate combined use of methotrexate with gold penicilamine hydroxychloroquine sulfasalazine or cytotoxic agents has not been studied any may increase the incidence of adverse effects rest and physiotherapy as indicated should be continued"
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAHesFs45O...#association
This association
http://www.w3.org/1999/02/22-rdf-syntax-ns#subject
has drug
https://identifiers.org/drugbank:DB00563
drugbank:DB00563
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAHesFs45O...#association
This association
http://www.w3.org/1999/02/22-rdf-syntax-ns#object
has disease
http://purl.obolibrary.org/obo/DOID_3590
DOID_3590
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAHesFs45O...#association
This association
https://w3id.org/biolink/vocab/relation
has relation
https://schema.org/TreatmentIndication
An indication for treating an underlying condition.
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAHesFs45O...#association
This association
https://w3id.org/biolink/vocab/association_type
has BioLink type
https://w3id.org/biolink/vocab...OrPhenotypicFeatureAssociation
ChemicalToDiseaseOrPhenotypicFeatureAssociation
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAHesFs45O...#association
This association
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
has type
http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement
association Statement
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAHesFs45O...#association
This association
http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate
has predicate
https://w3id.org/biolink/vocab/treats
treats
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAHesFs45O...#association
This association
https://w3id.org/biolink/vocab/provided_by
is provided by
https://w3id.org/um/NeuroDKG
NeuroDKG
.
This is the identifier for the assertion of this nanopublication.
http://purl.org/np/RAHesFs45O...#assertion
The assertion above
http://www.w3.org/ns/prov#wasAttributedTo
is attributed to
https://orcid.org/0000-0002-1468-3557
me (Leoni Bücken)
.
This is the identifier for this whole nanopublication.
http://purl.org/np/RAHesFs45O...
This nanopublication
http://purl.org/dc/terms/creator
is created by
https://orcid.org/0000-0002-1468-3557
me (Leoni Bücken)
.
This is the identifier for this whole nanopublication.
http://purl.org/np/RAHesFs45O...
This nanopublication
date and time when the nanopublication was created
http://purl.org/dc/terms/created
was created on
(this is a literal)
"2021-06-14T09:06:41.066+02:00"
.
This is the identifier for this whole nanopublication.
http://purl.org/np/RAHesFs45O...
This nanopublication
links to the assertion template that was used to create this nanopublication
https://w3id.org/np/o/ntemplate/wasCreatedFromTemplate
was created from the assertion template
http://purl.org/np/RAManV5GZI...
RAManV5GZI
.
This is the identifier for this whole nanopublication.
http://purl.org/np/RAHesFs45O...
This nanopublication
links to the provenance template that was used to create this nanopublication
https://w3id.org/np/o/ntemplate/wasCreatedFromProvenanceTemplate
was created from the provenance template
http://purl.org/np/RANwQa4ICW...
RANwQa4ICW
.
This is the identifier for this whole nanopublication.
http://purl.org/np/RAHesFs45O...
This nanopublication
links to the publication info template that was used to create this nanopublication
https://w3id.org/np/o/ntemplate/wasCreatedFromPubinfoTemplate
was created from the publication info template
http://purl.org/np/RAA2MfqdBC...
RAA2MfqdBC
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAHesFs45O...#sig
sig
http://purl.org/nanopub/x/hasSignatureTarget
has as target
This is the identifier for this whole nanopublication.
http://purl.org/np/RAHesFs45O...
this nanopublication
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAHesFs45O...#sig
sig
http://purl.org/nanopub/x/hasAlgorithm
has the algorithm
(this is a literal)
"RSA"
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAHesFs45O...#sig
sig
http://purl.org/nanopub/x/hasPublicKey
has the public key
(this is a literal)
"MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB"
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAHesFs45O...#sig
sig
http://purl.org/nanopub/x/hasSignature
has the signature
(this is a literal)
"DYipCtM1Z12KrwlD5TU8+quRWPmIH1y5tnsTxQC18G3eounHtNSG9WYnL//Erri2Szu5U1BDr92fCOAQF7CrAvkvhp7jCWho/uMKqgE0lobSEnKymug9MR1YhrnY4aqXm9gCspdio+ufBVPr6ZgYztNcX4KUSMsYqCZF+RSFspc="
.