RAayHgg0rw
Full identifier: http://purl.org/np/RAayHgg0rwyy3VekvzOBUQRTWgFievCUPaLwH4aLWhYO4
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Status
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Nanopublication
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAayHgg0rw...#association
This association
http://www.w3.org/2000/01/rdf-schema#label
has label
(this is a literal)
"Olanzapine was FDA approved for the treatment of schizophrenia and bipolar disorder only. It is an atypical antagonist of D2 and D4 receptors which determines a decrease in craving for alcohol. The DRD4 gene of dopamine presents a VNTR polymorphism, with a number of repetitions that varies from 2 to 11 which allows for the division of individuals in two subgroups: those with a number of repetitions between 2 and 6, classified as DRD4 S and those with more than 7 repetitions, classified as DRD4 L. Association studies between this variation and AUD have showed that individuals who carry the L allele exhibit greater craving after alcohol intake,50. Another study has investigated the association olanzapine-DRD4 showing that olanzapine reduces craving to the L allele carriers only, while no benefits were observed in S allele carriers."
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAayHgg0rw...#association
This association
http://www.w3.org/1999/02/22-rdf-syntax-ns#subject
has drug
https://identifiers.org/DRUGBANK:DB00334
DRUGBANK:DB00334
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAayHgg0rw...#association
This association
http://www.w3.org/1999/02/22-rdf-syntax-ns#object
has disease
http://purl.obolibrary.org/obo/DOID_1574
DOID_1574
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAayHgg0rw...#association
This association
https://w3id.org/biolink/vocab/relation
has relation
https://w3id.org/um/neurodkg/OffLabelIndication
An indication found in off-label drug uses
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAayHgg0rw...#association
This association
https://w3id.org/biolink/vocab/publications
has publications
https://pubmed.ncbi.nlm.nih.gov/29912214
pubmed.ncbi.nlm.nih.gov/29912214
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAayHgg0rw...#association
This association
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
has type
http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement
association Statement
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAayHgg0rw...#association
This association
http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate
has predicate
https://w3id.org/biolink/vocab/treats
treats
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAayHgg0rw...#association
This association
https://w3id.org/biolink/vocab/provided_by
is provided by
https://w3id.org/um/NeuroDKG
NeuroDKG
.
This is a local identifier that was minted when the nanopublication was created.
http://purl.org/np/RAayHgg0rw...#association
association
https://w3id.org/biolink/vocab/has_population_context
has_population_context
This is a local identifier that was minted when the nanopublication was created.
http://purl.org/np/RAayHgg0rw...#context
context
.
This is a local identifier that was minted when the nanopublication was created.
http://purl.org/np/RAayHgg0rw...#context
context
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
type
https://w3id.org/biolink/vocab/Cohort
Cohort
.
This is a local identifier that was minted when the nanopublication was created.
http://purl.org/np/RAayHgg0rw...#context
context
http://www.w3.org/2000/01/rdf-schema#label
label
"adults"
.
This is the identifier for the assertion of this nanopublication.
http://purl.org/np/RAayHgg0rw...#assertion
The assertion above
http://www.w3.org/ns/prov#generatedAtTime
generatedAtTime
(this is a literal)
"2021-08-26T09:18:29.198055"
.
This is the identifier for this whole nanopublication.
http://purl.org/np/RAayHgg0rw...
This nanopublication
links to the assertion template that was used to create this nanopublication
https://w3id.org/np/o/ntemplate/wasCreatedFromTemplate
was created from the assertion template
http://purl.org/np/RAhNHZw6Ur...
RAhNHZw6Ur
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAayHgg0rw...#sig
sig
http://purl.org/nanopub/x/hasSignatureTarget
has as target
This is the identifier for this whole nanopublication.
http://purl.org/np/RAayHgg0rw...
this nanopublication
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAayHgg0rw...#sig
sig
http://purl.org/nanopub/x/hasAlgorithm
has the algorithm
(this is a literal)
"RSA"
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAayHgg0rw...#sig
sig
http://purl.org/nanopub/x/hasPublicKey
has the public key
(this is a literal)
"MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCamPJb4SzqpLXn//XJ5dlVfzz6QI+RPmiJTLXF/by2JR7sHMKRsCQDFsYMlq8zGHghOIkjRP9dpLZUtZzUcHt3MXiFKEPo8eGzUe9p+JXKFC8xxkJr94z2vq6IdMf71Iu1GH8SeDAKt/DgYO4zNaw8VuXvxnZRewKZSA+u8zWPVwIDAQAB"
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAayHgg0rw...#sig
sig
http://purl.org/nanopub/x/hasSignature
has the signature
(this is a literal)
"Xul0Er1OEZlq+dVjbQ0m1pCd5STdOYyyHJARC23oqe/5lhRL5V1pr6zj39fii3udiM/oFfnA67tJ2ToNRVXdbaWJ1UlSjx04RpgdSwAQUQcNm57ILUyuwyImpyCBmkQ4q1t5r9ie/+FSFHAXAtrok87vzn6Aarb0u4QuYXZyhV4="
.
This is the identifier for this whole nanopublication.
http://purl.org/np/RAayHgg0rw...
this nanopublication
http://www.w3.org/ns/prov#generatedAtTime
generatedAtTime
(this is a literal)
"2021-08-26T09:18:29.198055"
.
This is the identifier for this whole nanopublication.
http://purl.org/np/RAayHgg0rw...
this nanopublication
http://www.w3.org/ns/prov#wasAttributedTo
wasAttributedTo
https://orcid.org/0000-0002-7641-6446
0000-0002-7641-6446
.
References