STAYAHEAD AlphaFold-2 Mutational Variant Dataset

https://w3id.org/np/RAVLW4m4-aEKD5vnkvzf-hpqsQJQOi7Dw3DXGFqesX9hc

 STAYAHEAD AlphaFold-2 Mutational Variant Dataset Dataset FAIRDigitalObject ▼ comment... approve/disapprove... edit as derived nanopublication... create new with same template...

This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF

STAYAHEAD_AF

http://www.w3.org/1999/02/22-rdf-syntax-ns#type is a https://w3id.org/fdof/ontology#FAIRDigitalObject FAIR Digital Object (FDO) .

This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF

STAYAHEAD_AF

http://www.w3.org/2000/01/rdf-schema#label has the label (this is a literal)

"STAYAHEAD AlphaFold-2 Mutational Variant Dataset"

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This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF

STAYAHEAD_AF

http://www.w3.org/2000/01/rdf-schema#comment has description (this is a literal)

"The resource centers on the RBD of the ancestral Wuhan-Hu-1 spike protein and includes a systematically generated set of all possible single-point missense variants (3,705 in total). All variants are annotated with structural descriptors derived from AlphaFold-2 predicted structures and augmented with sequence-based biophysical predictors such as disorder, flexibility, and amyloid aggregation propensity from the Bio2Byte suite. To complement structural predictions, empirical measurements of ACE2 binding affinity and surface expression levels were integrated for each 1-step variant, based on deep mutational scanning (DMS) data published by Starr et al. This pairing of theoretical and experimental annotations provides a foundation for analyzing structure–function relationships across the spike mutational landscape and supports downstream applications in protein modeling, variant characterization, and structure-guided surveillance."

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This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF

STAYAHEAD_AF

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Dataset

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This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF

STAYAHEAD_AF

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https://osf.io/9tj6b

9tj6b

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STAYAHEAD_AF

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https://osf.io/9tj6b

9tj6b

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csv

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9tj6b

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CC BY 4.0 | Attribution 4.0 International

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https://osf.io/9tj6b

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"2024"

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This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF

STAYAHEAD_AF

http://purl.org/dc/terms/creator has creator https://orcid.org/0009-0004-2188-0817

Max van den Boom

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This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF

STAYAHEAD_AF

http://purl.org/dc/terms/contributor has contributor https://orcid.org/0000-0001-8888-635X

Erik Schultes

.

This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF

STAYAHEAD_AF

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"info@health-holland.com"

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STAYAHEAD_AF

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en

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STAYAHEAD_AF

http://purl.org/dc/terms/subject has domain http://aims.fao.org/aos/agrovoc/c_4318

Life Science

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STAYAHEAD_AF

http://purl.org/dc/terms/publisher has publisher https://ror.org/056cwr036

056cwr036

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STAYAHEAD_AF

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"v1.0"

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This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../STAYAHEAD_AF

STAYAHEAD_AF

https://schema.org/funder has funder https://ror.org/056cwr036

056cwr036

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This is the identifier for the assertion of this nanopublication. https://w3id.org/np/RAVLW4m4-a.../assertion The assertion above http://www.w3.org/ns/prov#wasAttributedTo is attributed to https://orcid.org/0009-0004-2188-0817

Max van den Boom

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This is the identifier for this whole nanopublication. https://w3id.org/np/RAVLW4m4-a... This nanopublication http://purl.org/dc/terms/creator is created by https://orcid.org/0009-0004-2188-0817

Max van den Boom

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This is the identifier for this whole nanopublication. https://w3id.org/np/RAVLW4m4-a... This nanopublication http://purl.org/dc/terms/license is published under the license https://creativecommons.org/licenses/by/4.0/

Attribution 4.0 International (CC BY 4.0)

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https://orcid.org/0009-0004-2188-0817

Max van den Boom

http://xmlns.com/foaf/0.1/name has the name (this is a literal)

"Max van den Boom"

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"2025-07-11T14:14:10.950Z"

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RAc1AU2eoL

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RA7lSq6MuK

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RA0J4vUn_d

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RAukAcWHRD

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STAYAHEAD_AF

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CC BY 4.0 | Attribution 4.0 International

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"CC BY 4.0 | Attribution 4.0 International - Using this licence you are free to share and adapt the resource but you must ..."

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"gykUctN8nkBBr9d68apeIgXdcT/FwC5n3BbeW+52947il7ollGLS8IpiGMJOupnghiDoiMwvfscC/OkAgEASTGDt3ezQLIX3qEXW1hUTM6EfKtseYKeOvzKjQpSKEwV7W/K4FDp7yVKd3ZHOY38zXpHuah6mJur2wxOPk/V3I+U="

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This is a local identifier minted within the nanopublication. https://w3id.org/np/RAVLW4m4-a.../sig

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http://purl.org/nanopub/x/signedBy is signed by https://orcid.org/0009-0004-2188-0817

Max van den Boom

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This is the identifier for this whole nanopublication. https://w3id.org/np/RAVLW4m4-a... This nanopublication http://purl.org/nanopub/x/wasCreatedAt was created at https://nanodash.knowledgepixels.com/

nanodash.knowledgepixels.com

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Max van den Boom, 11 Jul 2025, 14:14:10 UTC

References