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sig

Full identifier: http://purl.org/np/RAJGZCKJJAKWUHX8E7EktwNrrfblpevOYvvbm-2dn1564#sig

Minted in Nanopublication

RAJGZCKJJA comment approve/disapprove edit as derived nanopublication create new with same template

This is a local identifier minted within the nanopublication. http://purl.org/np/RAJGZCKJJA...#association This association http://www.w3.org/2000/01/rdf-schema#label has label (this is a literal)

"Currently, there are no FDA-approved pharmacotherapies available for CUD, though a number (eg, cannabinoids, antidepressants, anxiolytics, and glutamatergic modulators) have been proposed for off-label use. We identified 12 trials examining psychopharmacological interventions for the treatment of cannabis use disorder. Trials examined antidepressants (ie, escitalopram, fluoxetine, bupropion, nefazodone, venlafaxine, vilazodone), antipsychotics (ie, clozapine, ziprasidone), buspirone, mood stabilizers (ie, divalproex, lithium), and atomoxetine. Overall, studies found that antidepressants as a class were less effective than placebo for the achievement of abstinence (moderate SOE). There was no difference between antidepressants (moderate SOE) or buspirone (low SOE) and placebo in reducing overall cannabis use or retention in treatment. We found low strength evidence of no difference from placebo for antidepressants or buspirone on harms. Antidepressant medications did not impact secondary outcomes (low SOE). Findings for all other psychopharmacotherapies and drug/outcome combinations were either insufficient or were not identified in the current literature."

This is a local identifier minted within the nanopublication. http://purl.org/np/RAJGZCKJJA...#association This association http://www.w3.org/1999/02/22-rdf-syntax-ns#subject has drug http://identifiers.org/drugbank/DB00363

DB00363

This is a local identifier minted within the nanopublication. http://purl.org/np/RAJGZCKJJA...#association This association http://www.w3.org/1999/02/22-rdf-syntax-ns#object has disease http://purl.obolibrary.org/obo/MONDO_0005689

MONDO_0005689

This is a local identifier minted within the nanopublication. http://purl.org/np/RAJGZCKJJA...#association This association https://w3id.org/biolink/vocab/relation has relation http://purl.obolibrary.org/obo/NCIT_C94303

NCIT_C94303

This is a local identifier minted within the nanopublication. http://purl.org/np/RAJGZCKJJA...#association This association https://w3id.org/biolink/vocab/publications has publications http://www.ncbi.nlm.nih.gov/pubmed/32227801

pubmed/32227801

This is a local identifier minted within the nanopublication. http://purl.org/np/RAJGZCKJJA...#association This association http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate has predicate https://w3id.org/biolink/vocab/treats treats .

http://identifiers.org/drugbank/DB00363

DB00363

https://w3id.org/biolink/vocab/category is a https://w3id.org/biolink/vocab/Drug Drug .

http://purl.obolibrary.org/obo/MONDO_0005689

MONDO_0005689

https://w3id.org/biolink/vocab/category is a https://w3id.org/biolink/vocab/Disease Disease .

http://identifiers.org/drugbank/DB00363 DB00363 http://www.w3.org/1999/02/22-rdf-syntax-ns#type type https://w3id.org/biolink/vocab/Drug Drug .

http://identifiers.org/drugbank/DB00363 DB00363 http://www.w3.org/2000/01/rdf-schema#label label "Clozapine" .

http://purl.obolibrary.org/obo/MONDO_0005689 MONDO_0005689 http://www.w3.org/1999/02/22-rdf-syntax-ns#type type https://w3id.org/biolink/vocab/Disease Disease .

http://purl.obolibrary.org/obo/MONDO_0005689 MONDO_0005689 http://www.w3.org/2000/01/rdf-schema#label label "Cannabis dependence" .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RAJGZCKJJA...#association association http://www.w3.org/1999/02/22-rdf-syntax-ns#type type https://w3id.org/biolink/vocab...OrPhenotypicFeatureAssociation ChemicalToDiseaseOrPhenotypicFeatureAssociation .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RAJGZCKJJA...#association association https://w3id.org/biolink/vocab/aggregator_knowledge_source aggregator_knowledge_source https://w3id.org/biolink/infores/knowledge-collaboratory knowledge-collaboratory .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RAJGZCKJJA...#association association https://w3id.org/biolink/vocab/category category https://w3id.org/biolink/vocab...OrPhenotypicFeatureAssociation ChemicalToDiseaseOrPhenotypicFeatureAssociation .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RAJGZCKJJA...#association association https://w3id.org/biolink/vocab/has_population_context has_population_context This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RAJGZCKJJA...#context context .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RAJGZCKJJA...#context context http://www.w3.org/1999/02/22-rdf-syntax-ns#type type https://w3id.org/biolink/vocab/Cohort Cohort .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RAJGZCKJJA...#context context http://www.w3.org/2000/01/rdf-schema#label label "Adults" .

This is a local identifier that was minted when the nanopublication was created. http://purl.org/np/RAJGZCKJJA...#context context https://w3id.org/biolink/vocab/category category https://w3id.org/biolink/vocab/Cohort Cohort .

This is the identifier for the assertion of this nanopublication. http://purl.org/np/RAJGZCKJJA...#assertion The assertion above http://www.w3.org/ns/prov#wasAttributedTo

wasAttributedTo

https://orcid.org/0000-0002-7641-6446

0000-0002-7641-6446

This is the identifier for this whole nanopublication. http://purl.org/np/RAJGZCKJJA... This nanopublication links to the assertion template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromTemplate was created from the assertion template http://purl.org/np/RAhNHZw6Ur...

RAhNHZw6Ur

This is a local identifier minted within the nanopublication. http://purl.org/np/RAJGZCKJJA...#sig

sig

http://purl.org/nanopub/x/hasSignatureTarget has as target This is the identifier for this whole nanopublication. http://purl.org/np/RAJGZCKJJA... this nanopublication .

This is a local identifier minted within the nanopublication. http://purl.org/np/RAJGZCKJJA...#sig

sig

http://purl.org/nanopub/x/hasAlgorithm has the algorithm (this is a literal)

"RSA"

This is a local identifier minted within the nanopublication. http://purl.org/np/RAJGZCKJJA...#sig

sig

http://purl.org/nanopub/x/hasPublicKey has the public key (this is a literal)

"MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCR9fz0fKCdWOWC+pxhkQhEM/ppbdIYe5TLSdj+lJzSlv9mYBaPgrzVezSwwbmhlHBPDZa4/vHycU315BdmUGq+pXllp9+rWFfrb+kBJwhZjpG6BeyyXBsRFz4jmQVxl/ZYHilQTh/XalYzKkEAyTiEMPee4Kz61PaWOKH24CsnOQIDAQAB"

This is a local identifier minted within the nanopublication. http://purl.org/np/RAJGZCKJJA...#sig

sig

http://purl.org/nanopub/x/hasSignature has the signature (this is a literal)

"f59YvDXkKe/Pep61gPdEVF5PI3FvElFEkYqQNaaNqCNDBueeVKeDM7YBv/G8iB7ziN+c9Jru0v3EKKYrHJEIGY8yz4t4BhXuEVTEcnYpF1JnyxbmbK29k9q5pINGvBReDqeQZZ+ePaxmJJuN6UrGVssFDn+fD1U5pcMw4Br/Jn0="

https://w3id.org/biolink/vocab/

vocab

http://purl.org/pav/version

version

(this is a literal)

"2.3.0"

This is the identifier for this whole nanopublication. http://purl.org/np/RAJGZCKJJA...

this nanopublication

http://www.w3.org/ns/prov#generatedAtTime

generatedAtTime

(this is a literal)

"2022-09-16T11:51:54.328797"

(xsd:dateTime) .

This is the identifier for this whole nanopublication. http://purl.org/np/RAJGZCKJJA...

this nanopublication

http://www.w3.org/ns/prov#wasAttributedTo

wasAttributedTo

https://orcid.org/0000-0002-1501-1082

Vincent Emonet

Vincent Emonet, 16 Sep 2022, 11:51:54 UTC

References

Nanopublication	Part	Subject	Predicate	Object	Published By	Published On
http://purl.org/np/RAJGZCKJJA... RAJGZCKJJA	links a nanopublication to its pubinfo http://www.nanopub.org/nschema#hasPublicationInfo pubinfo	sig	http://purl.org/nanopub/x/hasAlgorithm hasAlgorithm	RSA	Vincent Emonet	2022-09-16T11:51:54.328Z
http://purl.org/np/RAJGZCKJJA... RAJGZCKJJA	links a nanopublication to its pubinfo http://www.nanopub.org/nschema#hasPublicationInfo pubinfo	sig	http://purl.org/nanopub/x/hasPublicKey hasPublicKey	MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCR9fz0fKCdWOWC+pxhkQhEM/ppbdIYe5TLSdj+lJzSlv9mYBaPgrzVezSwwbmhlHBPDZa4/vHycU315BdmUGq+pXllp9+rWFfrb+kBJwhZjpG6BeyyXBsRFz4jmQVxl/ZYHilQTh/XalYzKkEAyTiEMPee4Kz61PaWOKH24CsnOQIDAQAB	Vincent Emonet	2022-09-16T11:51:54.328Z
http://purl.org/np/RAJGZCKJJA... RAJGZCKJJA	links a nanopublication to its pubinfo http://www.nanopub.org/nschema#hasPublicationInfo pubinfo	sig	http://purl.org/nanopub/x/hasSignature hasSignature	f59YvDXkKe/Pep61gPdEVF5PI3FvElFEkYqQNaaNqCNDBueeVKeDM7YBv/G8iB7ziN+c9Jru0v3EKKYrHJEIGY8yz4t4BhXuEVTEcnYpF1JnyxbmbK29k9q5pINGvBReDqeQZZ+ePaxmJJuN6UrGVssFDn+fD1U5pcMw4Br/Jn0=	Vincent Emonet	2022-09-16T11:51:54.328Z
http://purl.org/np/RAJGZCKJJA... RAJGZCKJJA	links a nanopublication to its pubinfo http://www.nanopub.org/nschema#hasPublicationInfo pubinfo	sig	http://purl.org/nanopub/x/hasSignatureTarget hasSignatureTarget	http://purl.org/np/RAJGZCKJJA... RAJGZCKJJA	Vincent Emonet	2022-09-16T11:51:54.328Z

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