RAJ_wIH5Q8
Full identifier: http://purl.org/np/RAJ_wIH5Q8hc-PhR4wSLNcXLgaWO6Kp5wHrKZhkyOPn84
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Status
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Nanopublication
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAJ_wIH5Q8...#association
This association
http://www.w3.org/2000/01/rdf-schema#label
has label
(this is a literal)
"Olanzapine was FDA approved for the treatment of schizophrenia and bipolar disorder only. It is an atypical antagonist of D2 and D4 receptors which determines a decrease in craving for alcohol. The DRD4 gene of dopamine presents a VNTR polymorphism, with a number of repetitions that varies from 2 to 11 which allows for the division of individuals in two subgroups: those with a number of repetitions between 2 and 6, classified as DRD4 S and those with more than 7 repetitions, classified as DRD4 L. Association studies between this variation and AUD have showed that individuals who carry the L allele exhibit greater craving after alcohol intake,50. Another study has investigated the association olanzapine-DRD4 showing that olanzapine reduces craving to the L allele carriers only, while no benefits were observed in S allele carriers."
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAJ_wIH5Q8...#association
This association
http://www.w3.org/1999/02/22-rdf-syntax-ns#subject
has drug
http://identifiers.org/drugbank/DB00334
DB00334
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAJ_wIH5Q8...#association
This association
http://www.w3.org/1999/02/22-rdf-syntax-ns#object
has disease
http://purl.obolibrary.org/obo/DOID_1574
DOID_1574
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAJ_wIH5Q8...#association
This association
https://w3id.org/biolink/vocab/relation
has relation
http://purl.obolibrary.org/obo/NCIT_C94303
NCIT_C94303
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAJ_wIH5Q8...#association
This association
https://w3id.org/biolink/vocab/publications
has publications
http://www.ncbi.nlm.nih.gov/pubmed/29912214
pubmed/29912214
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAJ_wIH5Q8...#association
This association
http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate
has predicate
https://w3id.org/biolink/vocab/treats
treats
.
http://purl.obolibrary.org/obo/DOID_1574
DOID_1574
http://www.w3.org/2000/01/rdf-schema#label
label
"alcohol use disorder"
.
This is a local identifier that was minted when the nanopublication was created.
http://purl.org/np/RAJ_wIH5Q8...#association
association
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
type
https://w3id.org/biolink/vocab...OrPhenotypicFeatureAssociation
ChemicalToDiseaseOrPhenotypicFeatureAssociation
.
This is a local identifier that was minted when the nanopublication was created.
http://purl.org/np/RAJ_wIH5Q8...#association
association
https://w3id.org/biolink/vocab/aggregator_knowledge_source
aggregator_knowledge_source
https://w3id.org/biolink/infores/knowledge-collaboratory
knowledge-collaboratory
.
This is a local identifier that was minted when the nanopublication was created.
http://purl.org/np/RAJ_wIH5Q8...#association
association
https://w3id.org/biolink/vocab/category
category
https://w3id.org/biolink/vocab...OrPhenotypicFeatureAssociation
ChemicalToDiseaseOrPhenotypicFeatureAssociation
.
This is a local identifier that was minted when the nanopublication was created.
http://purl.org/np/RAJ_wIH5Q8...#association
association
https://w3id.org/biolink/vocab/has_population_context
has_population_context
This is a local identifier that was minted when the nanopublication was created.
http://purl.org/np/RAJ_wIH5Q8...#context
context
.
This is a local identifier that was minted when the nanopublication was created.
http://purl.org/np/RAJ_wIH5Q8...#context
context
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
type
https://w3id.org/biolink/vocab/Cohort
Cohort
.
This is a local identifier that was minted when the nanopublication was created.
http://purl.org/np/RAJ_wIH5Q8...#context
context
http://www.w3.org/2000/01/rdf-schema#label
label
"adults"
.
This is a local identifier that was minted when the nanopublication was created.
http://purl.org/np/RAJ_wIH5Q8...#context
context
https://w3id.org/biolink/vocab/category
category
https://w3id.org/biolink/vocab/Cohort
Cohort
.
This is the identifier for the assertion of this nanopublication.
http://purl.org/np/RAJ_wIH5Q8...#assertion
The assertion above
http://www.w3.org/ns/prov#wasAttributedTo
wasAttributedTo
https://orcid.org/0000-0002-7641-6446
0000-0002-7641-6446
.
This is the identifier for this whole nanopublication.
http://purl.org/np/RAJ_wIH5Q8...
This nanopublication
links to the assertion template that was used to create this nanopublication
https://w3id.org/np/o/ntemplate/wasCreatedFromTemplate
was created from the assertion template
http://purl.org/np/RAhNHZw6Ur...
RAhNHZw6Ur
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAJ_wIH5Q8...#sig
sig
http://purl.org/nanopub/x/hasSignatureTarget
has as target
This is the identifier for this whole nanopublication.
http://purl.org/np/RAJ_wIH5Q8...
this nanopublication
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAJ_wIH5Q8...#sig
sig
http://purl.org/nanopub/x/hasAlgorithm
has the algorithm
(this is a literal)
"RSA"
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAJ_wIH5Q8...#sig
sig
http://purl.org/nanopub/x/hasPublicKey
has the public key
(this is a literal)
"MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCR9fz0fKCdWOWC+pxhkQhEM/ppbdIYe5TLSdj+lJzSlv9mYBaPgrzVezSwwbmhlHBPDZa4/vHycU315BdmUGq+pXllp9+rWFfrb+kBJwhZjpG6BeyyXBsRFz4jmQVxl/ZYHilQTh/XalYzKkEAyTiEMPee4Kz61PaWOKH24CsnOQIDAQAB"
.
This is a local identifier minted within the nanopublication.
http://purl.org/np/RAJ_wIH5Q8...#sig
sig
http://purl.org/nanopub/x/hasSignature
has the signature
(this is a literal)
"EZH5DT4K3l3uk6H65DHWAFQwIG+q31cWFOWWvUTRFQEbfkP87pLflbnQY7oS7uK9Y2L1/1z7o1EAR8ztBHhZBiyhtO0V2nHq+BNRb4bTQw5R6rSh7tLcxWc0nWl4tfQKmTRJFa/E1ZlhMXlourWMY1+X7ekIYjn7T3WtuTCDpnQ="
.
https://w3id.org/biolink/vocab/
vocab
http://purl.org/pav/version
version
(this is a literal)
"2.3.0"
.
This is the identifier for this whole nanopublication.
http://purl.org/np/RAJ_wIH5Q8...
this nanopublication
http://www.w3.org/ns/prov#generatedAtTime
generatedAtTime
(this is a literal)
"2022-09-16T11:54:35.529379"
.
This is the identifier for this whole nanopublication.
http://purl.org/np/RAJ_wIH5Q8...
this nanopublication
http://www.w3.org/ns/prov#wasAttributedTo
wasAttributedTo
https://orcid.org/0000-0002-1501-1082
Vincent Emonet
.
References